Interleukin-2 (IL-2) upregulates BAG-1 gene expression through serine- rich region within IL-2 receptor beta c chain
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چکیده
منابع مشابه
Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.
We demonstrate that purified interleukin 2 (IL-2) can directly upregulate IL-2 receptor expression on phytohemagglutinin-activated T lymphocytes maintained in culture until IL-2 receptor expression had markedly declined. The IL-2-induced increase in IL-2 receptor number is maximal within 12 hr, requires new RNA and protein synthesis, and is mediated by an interaction of ligand with the high-aff...
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ژورنال
عنوان ژورنال: Blood
سال: 1996
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v88.11.4118.4118